FH - Familial Hypercholesterolemia

Homozygous FH
FH Global Summit 2014a

Two FDA-approved drugs for FH are extremely unaffordable. Juxtapid costs $350,000 a year. Kynamro costs $175,000 a year.

FH Global Summit 2014b


Repatha 140 mg + Rosuvastatin 40 mg + Ezetimibe 10 mg: LDLc from 388 to 74.


Repatha 140 mg + Pravastatin 40 mg: LDLc 225 to 82. 

HeFH - KS
Capture - HeFH-KaSt
Capture - KaStHeFHPraluent


Ezetimibe 10 mg + Repatha 140 mg (statin intolerant): LDLc 241 to 52.



Severe Familial Hypertriglyceredemia

This slide below is not familial hypercholesterolemia but severe familial hypertriglyceredemia.

Familial Hypertriglyceridemia

The above is an example of someone with extremely high triglycerides. 

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